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Academic activities 2020

2020

Articles

  • Akimoto M, Yamamoto Y, Watanabe S, Yamaga H, Yoshida K, Wakabayashi K, Tahara Y, Horie N, Fujimoto K, Kusakari K, Kamiya K, Kojima K, Kawakami T, Kojima H, Ono A, Kasahara T, Fujita M: Oxidation of a cysteine-derived nucleophilic reagent by dimethyl sulfoxide in the amino acid derivative reactivity assay. J Appl Toxicol. 2020 Feb 12.
  • Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A:Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development. ALTEX. 2020;37(3):364-394. doi: 10.14573/altex.2001241.
  • Kimura Y, Yasuno R, Watanabe M, Kobayashi M, Iwaki T, Fujimura C, Ohmiya Y, Yamakage K, Nakajima Y, Kobayashi M, Mashimo N, Takagi Y, Omori T, Corsini E, Germolec D, Inoue T, Rogen EL, Kojima H, Aiba S: An international validation study of the IL-2 Luc assay for evaluating the potential immunotoxic effects of chemicals on T cells and a proposal for reference data for immunotoxic chemicals. Toxicol In Vitro. 2020;66:104832.
  • Mizoi K, Hosono M, Kojima H, Ogihara T: Establishment of a primary human hepatocyte spheroid system for evaluating metabolic toxicity using dacarbazine under conditions of CYP1A2 induction. Drug Metab Pharmacokinet . 2020,35(2):201-206. doi: 10.1016/j.dmpk.2019.11.002.
  • Mizoi K, Arakawa H, Yano K, Koyama S, Kojima H, Ogihara T:Utility of Three-Dimensional Cultures of Primary Human Hepatocytes (Spheroids) as Pharmacokinetic Models. JBiomedicines. 2020;8(10):374. doi: 10.3390/biomedicines8100374.
  • Kato Y, Yamamoto N, Hiramatsu N, Sato A, Kojima H:Inhouse Fabrication of a Reconstructed Human Corneal Epithelium Model for Use in Testing for Eye Irritation Potential. Applied in Vitro Toxicology, 2020;6(3), doi: 10.1089/aivt.2020.0003.

Presentations, Speeches

  • Ashikaga T, Narita K, Okutomi H, Kawakami K, Sui H: Effectiveness of h-CLAT, an In Vitro Skin Sensitization Test Method, in Evaluating Respiratory Sensitizers, 59th Annual Meeting of SOT (2020.3.15-19, Anaheim,CA,USA, Virtual)
  • Kojima H, Ishida S: Challenge of standardization in the AMED-MPS project, Global Summit on Regulatory Science (GSRS20)(2020.9.30, USA, Virtual)
  • Kojima H: Establishment of the Asian Consortium for Three R’s,The 26th Frontier Scientists Workshop (2020.12. 18, Korea, Virtual)
  • Kojima H: Establishment of the Asian Consortium for Three R’s with SAAE-I, International Webinar & 3rd National Conference of the Society for Alternatives to Animal Experiments (IWSAAE& NCSAAE-2020) (2020.12.28, India, Virtual)