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International acceptance on Japanese test methods validated by JaCVAM

Test Method Accepted TG Year
Skin Sensitisation: Local Lymph Node Assay: DA OECD TG442A 2010
Skin Sensitisation: Local Lymph Node Assay: BrdU-ELISA or –FCM  OECD TG442B 2010
In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method, LabCyte EPI-Model24 OECD TG439 2013
Ros (Reactive Oxygen Species) Assay for Photosafety  ICH S10 2013
In Vivo Mammalian Alkaline Comet Assay OECD TG489 2014
Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage  OECD TG 491 2015
Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists, The Stably Transfected TA (STTA) assay using the (h) ERα-HeLa-9903 cell line OECD TG 455 2015
Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals, AR-Ecoscreen OECD TG458 2016
In Vitro Skin Sensitisation Assays addressing the Key Event on Activation of Dendritic Cells on the Adverse Outcome Pathway for Skin Sensitisation, Human Cell Line Activation Test (h-CLAT)  OECD TG442E 2016
In Vitro Bhas 42 Cell Transformation Assay (Bhas 42 CTA) OECD GD231 2016
In Vitro Skin Sensitisation Assays addressing the Key Event on Activation of Dendritic Cells on the Adverse Outcome Pathway for Skin Sensitisation, IL-8 Luc assay OECD TG442E 2017
Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage, LabCyte Cornea-Model24 OECD TG492 2018
Vitrigel-Eye Irritancy Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage OECD TG494 2019
In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method, LabCyte EPI-Model24 OECD TG431 2019
In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Covalent Binding to Proteins, ADRA (Amino acid Derivative Reactivity Assay) OECD TG442C 2019
Ros Assay for Photoreactivity  OECD TG495 2019

International acceptance on non-Japanese test methods contributed by JaCVAM

Test Method Accepted TG Year
Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants OECD TG460 2017
BG1Luc Estrogen Receptor Transactivation Test Method for Identifying Estrogen Receptor Agonists and Antagonists OECD TG457 2012
Skin Sensitisation OECD TG429 2010
Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage OECD TG437 2009
Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage OECD TG438 2009
In Vitro Membrane Barrier Test Method for Skin Corrosion OECD TG435 2006