MENU

Update on JaCVAM

Completion
On going
Pending or Cancellation
not yet started

You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
01
Corrosivity Test
01
Transcutaneous Electrical Resistance Test Method (TER)
EURL ECVAM

EURL ECVAM
& ICCVAM


OECD TG
No. 430
Oct.2017

02
Reconstructed Human Epidermis (RHE) Test Method, EpiSkin™, EpiDerm™ SCT, SkinEthics™ RHE, epiCS®
EURL ECVAM

EURL ECVAM
& ICCVAM


OECD TG
No. 431
Jun.2017

03
Reconstructed Human Epidermis (RHE) Test Method, LabCyte EPI- MODEL24 SCT
JaCVAM

JaCVAM





04
In vitro Membrane Barrier Test Method
EURL ECVAM

EURL ECVAM
& ICCVAM


OECD TG
No. 435
Oct.2017

05
Reconstructed Human Epidermis (RHE) Test Method, Vitrolife-skinTM
JSAAE

JaCVAM





Aug.2008

You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
04
Eye Irritation Test
01
OECD TG
No.405 (2012)


ICCVAM



OECD TG
No. 405
Jan.2014

02
Bovine Corneal Opacity and Permeability Test Method (BCOP)
EURL ECVAM
& ICCVAM
EURL ECVAM
& ICCVAM


OECD TG
No. 437
Jan.2014

03
Isolated Chicken Eye Test Method
EURL ECVAM
& ICCVAM
EURL ECVAM
& ICCVAM


OECD
TG438
Nov.2019

04
Fluorescein Leakage (FL)Test Method
EURL ECVAM
& ICCVAM
EURL ECVAM



OECD
TG460
Jan.2013

05
Short Time Exposure In vitro Test Method
JaCVAM

ICCVAM



OECD
TG491
Mar.2016

06
Reconstructed Human Cornea-like Epithelium(RhCE) Test Method, EpiOcularTM EIT、SkinEthicsTM HCE EIT
Cosmetic Europe/
EURL ECVAM
EURL ECVAM



OECD TG
No. 492
Mar.2018

07
Reconstructed Human Cornea-like Epithelium(RhCE) Test Method, LabCyte CORNEA-MODEL24 EIT
JaCVAM

JaCVAM



Feb.2019

08
Reconstructed Human Cornea-like Epithelium(RhCE) Test Method, MCTT
KoCVAM

OECD





09
Vitrigel-EIT (Eye Irritancy Test Method)
JaCVAM

JaCVAM



OECD TG
No. 494


10
Cytosensor Microphysiometer (CM) Toxicity Test Method
EURL ECVAM

EURL ECVAM



OECD



11
Macromolecular Test Method
InVitro
International
EURL ECVAM



OECD TG
No. 496


12
SIRC-CVS (Crystal Violete Staining):TEA Assay
JaCVAM

JaCVAM







13
Reconstructed Human Epidermis (RHE) Test Method, MATREX
JaCVAM









You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
05
Skin Sensitization Test
01
LLNA
EURL ECVAM

ICCVAM



OECD TG
No. 429


02
rLLNA
EURL ECVAM &
ICCVAM
ICCVAM



Jan.2013

03
LLNA:DA
JSAAE

JaCVAM or
ICCVAM


OECD TG
No. 442A
Jan.2013

04
LLNA:BrdU-ELISA
JSAAE

JaCVAM or
ICCVAM


OECD TG
No. 442B
Jan.2013

05
LLNA:BrdU-FCM
KoCVAM

OECD





06
DPRA
EURL ECVAM

EURL ECVAM



OECD TG
No. 442C
Mar.2015

07
ADRA
JaCVAM

JaCVAM





08
KeratinoSenseTM Test Method
EURL ECVAM

EURL ECVAM



OECD TG
No. 442D
Aug.2015

09
LuSensTM Test Method
BASF

EURL ECVAM





Nov.2019

10
h-CLAT Method
JaCVAM &
EURL ECVAM
EURL ECVAM



OECD TG
No. 442E
Mar.2017

11
IL-8 Luc Assay
JaCVAM

JaCVAM





12
U-SENSTM Method
Loreal

EURL ECVAM



Nov.2018

13
SENS-ISTM Assay
ImmunoSearch

EURL ECVAM



OECD



14
GARDskin Test
3RsMC

EURL ECVAM



OECD



15
kDPRA
BASF

EURL ECVAM



OECD



16
EpiSensA
JaCVAM









You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
07
Acute Oral Toxicity Test
01
Cytotoxicity Test (Estimate Starting Doses for Acute Oral Systemic Toxicity Tests)
EURL ECVAM
& ICCVAM
ICCVAM



OECD GD
No. 129
Jun.2011

02
Cytotoxicity Test
(LD50 ≧ 2000mg/Kg)
EURL ECVAM

EURL ECVAM



EURL ECVAM
recommendation
Apr.2019

You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
08
Genotoxicity Test
01
OECD TG No.473,476,487,490


OECD



OECD TG
No. 473, 476, 487, 490


02
In vivo Mammalian Alkaline Comet Assay
JaCVAM

OECD



OECD TG
No. 489


03
Pig-a Assay
US FDA

OECD



OECD



04
Reconstructed Human Epidermis (RHE) Test Method
Cosmetic Europe/
EURL ECVAM








05
In vitro Mammalian Alkaline Comet Assay
JaCVAM









You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
09
Endcrine Disrupter Screening
01
VM7 Luc ER TA Assay
ICCVAM

ICCVAM



OECD TG
No. 455
Jan.2014

02
Stably Transfected Transactivation (STTA) Assay using the (h) ERα-HeLa-9903 cell line
NIHS & CERI

OECD



Dec.2016

03
ER-CALUX








04
AR-Ecoscreen
NIHS & CERI

OECD



OECD TG
No. 458
Feb.2019

05
AR-CALUX
EURL ECVAM

EURL ECVAM





06
22Rv1/MMTV
Korea

Korea





07
In vitro Estrogen Receptor Binding Assay
EPA, CERI

OECD



OECD TG
No. 493


08
CCi Assay
ICCVAM









09
MELN Assay
EURL ECVAM









You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
10
Embryonic Toxicoty Scrneeing
01
Embyonic Stem Cell Test
EURL ECVAM

EURL ECVAM







01
Hand1-Luc EST
JaCVAM

JaCVAM



OECD



You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
11
Metabolism
01
CYP Induction Method
EURL ECVAM

EURL ECVAM



OECD



02
PBK Model






OECD



You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
12
Immune Toxicity Test
01
IL-2 Luc Assay
JaCVAM









02
IL-1βLuc Assay
JaCVAM









You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
14
Pyrogen Screening Test
01
PBMC (Peripheral Blood Mononuclear Cell) Assay
EURL ECVAM

EURL ECVAM
or ICCVAM


Ph. Eur.



You can scroll horizontally.

Classification Test method Validation
study
Peer reviews
by experts
Protocol Test
guidelines
Recommendation
to government
15
Oral Toxicity Test
01
EpiOralTM