Mizumachi H,Watanabe M, Ikezumi M, Kajiwara M, Yasuda M, Mizuno M, Imai N, Sakuma M, Shibata M, Watanabe S, Motoyama J, Basketter D, Eskes C, Hoffmann S, Lehmann D, Ashikaga T, Sozu T, Takeyoshi M, Suzuki S, Miyazawa M, Kojima H: The inter-laboratory validation study of EpiSensA for predicting skin sensitization potential, J Appl Toxicol. 2024:44(4);510-525. doi: 10.1002/jat.4559.
Nishikawa A, Nagano K, Kojima H, Fukushima S, Ogawa K. Pathogenesis of chemically induced nasal cavity tumors in rodents: contribution to adverse outcome pathway, J Toxicol Pathol. 2024 ;37(1):11-27. doi: 10.1293/tox.2023-0098
Aoi T, Asaka I, Akutsu H, Ito Y, Kataoka K, Kanda Y, Kojima H, Sekino Y, Suemori H, Nakagawa M, Nakamura K, Nakamura Y, Fujii M, Furue M, Yamazaki D, Japanese Working Group for Consideration of Good Cell Culture Practice: Secondary Publication: Proposal for Points of Consideration for Pluripotent Stem Cell Culture, In Vitro Cellular & Developmental Biology – Animal.2024:60;563-568. https://doi.org/10.1007/s11626-024-00863-w
Yamamoto N, Hiramatsu N, kato Y, Sato A, Kojima H, Development of an Eye Irritation Test Method Using anIn‑House Fabrication of a Reconstructed Human Cornea‑like Epithelium Model for Eye Hazard Identification, IBioengineering 2024;11(4):302. https://doi.org/10.3390/bioengineering11040302
Ashikaga T, Hatano K, Iwasa H, Kinoshita K, Nakamura N, Ambe K, Tohkin M, Next Generation Risk Assessment Case Study: A Skin Sensitization Quantitative Risk Assessment for Bandrowski’s Base Existing in Hair Color Formulations, J. Cos. Sci. Soc, 2024;48(2):1-5.
Mathisen GH, Bearth A, Jones LB, Hoffmann S, Vist GE, Ames HM, Husøy T, Svendsen C, Tsaioun K, Ashikaga T, Bloch D, Cavoski A, Chiu WA, Davies HG, Giusti A, Hartung T, Hirabayashi Y, Hogberg HT, Joglekar R, Kojima H, Krishnan K, Kwon S, Osborne OJ, Roggen E, Rooney AA, Rousselle C, Sass JB, Sepai O, Simanainen U, Thayer KA, Tong W, Wikoff D, Wright F, Whaley P, Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology, Arch Toxicol, 2024 Jun 14. doi: 10.1007/s00204-024-03802-6.
Nishida A, Sawada Y, Arai R, Ishibashi N, Suzuo M, Ohno A, Ashikaga T, Iijima K, Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells, Front. Toxicol., 01 July 2024. https://doi.org/10.3389/ftox.2024.1293147.
Ashikaga T, Hatano K, Iwasa H Kinoshita K, Nakamura N, Ambe K, Tohkin M,Next Generation Risk Assessment Case Study:
A Skin Sensitization Quantitative Risk Assessmentfor Bandrowski’s Base Existing in Hair Color Formulations, Journal of Japanese Cosmetic Science Society, 2024;48(2):73-77.
Kasahara T, YamamotoY, Nakashima N, Imamura M, Mizumachi H, Suzuki S, Aiba S, Kimura Y, Ashikaga T, Kojima H, Ono A, Matsumoto K, Borderline Range Determined Using Data From Validation Study of Alternative Methods for Skin Sensitization: ADRA, IL-8 Luc Assay, and EpiSensA, Journal of Applied Toxicology, 2024; 0:1–8. https://doi.org/10.1002/jat.4712
Presentations, Speeches
Kojima H: Japanese Regulatory activities on 3D cell culture, International Conference on Advances in 3D Cell Culture (2024.2.3, Mumbai, India)
Ashikaga T, Ohno A, Arai R, Iijima K: Activation of THP-1 cells by mixed exposure to silicon dioxide nanomaterial
and skin sensitizer or febrile substance, SOT 63nd Annual Meeting(2024.3.12, Salt Lake City, USA)
Ishida S, Matsushita T, Sato K, Ashikaga T, Hirabayashi Y, Yamazaki D: Japanese approach to the proposal of an OECD Test Guideline using Gut-Liver MPS for the first pass effect analysis as a Context of Use of toxicokinetic simulator in chemical risk assessment, MPS World Summit 2024 (2024.6.13, Seattle, USA)
Ashikaga T, Tanabe I, Ishikawa S, Mizoguchi I, Yoshimoto T: Development of an in vitro respiratory sensitization test based on a concept of a co-culture system between humanbronchial epithelial cells and antigen presenting cells, LIVe 2024 (2024.6.20, Nice, France)
Tokunaga J, Kinoshita K, Ambe K, Yamada T, Ashikaga T, Tohkin M: Development of the regression model in machine learning to predict skin sensitization intensity and considerations for improving interpretability, 51st Annual Meeting of the Japanese Society of Toxicology (2024.7.3, Fukuoka, Japan)
Ashikaga T, Ohya K, Kato T, Kitagawa T, Kojima H, Sozu T, Hayashi K, Tachibana S, Masumori S, Mishima T, Kusunoki T, Shimizu J, Fushihara K, Miyazaki K: Validation study of pyrogen-detection system using immortalized human monocyte cell line, 51st Annual Meeting of the Japanese Society of Toxicology (2024.7.5, Fukuoka, Japan)
Iijima K, Yamashiro M, Sakamoto R, Ohno A, Ashikaga T: Evaluation of the ability to activate antigen-presenting cells and analysis of the activation mechanism for various types of zinc oxide nanoparticles, 51st Annual Meeting of the Japanese Society of Toxicology (2024.7.5, Fukuoka, Japan)
