Kojima H, Ikarashi Y, Nakada T, Yagami A, Sugibayashi K, Todo H, Hoshino Y, Iizuka N, Nakamura T, Sekizawa S, Shinoda K, Yagi M, Araki D, Sakaguchi H, Sasa H, Sugiyama M: Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-Drugs, Alternatives to Animal Testing, Springer, Singapore, pp.63-68, 2019.
Fujita M, Yamamoto Y, Watanabe S, Sugawara T, Wakabayashi K, Tahara Y, Horie N, Fujimoto K, Kusakari K, Kurokawa Y, Kawakami T, Kojima K, Kojima H, Ono A, Katsuoka Y, Tanabe H, Yokoyama H, Kasahara T： Cause of and countermeasures for oxidation of the cysteine-derived reagent used in the amino acid derivative reactivity assay, J Appl Toxicol. 2019;39(2):191-208. doi: 10.1002/jat.3707.
Mitachi T, Kouzui M, Maruyama R, Yamashita K, Ogata S, Kojima H, Itagaki H: Some non-sensitizers upregulate CD54 expression by activation of the NLRP3 inflammasome in THP-1 cells. J Toxicol Sci. 2019;44(3):213-224.
Kobayashi-Tsukumo H, Oiji K, Xie D, Sawada Y, Yamashita K, Ogata S, Kojima H, Itagaki H: Eliminating the contribution of lipopolysaccharide to protein allergenicity in the human cell-line activation test (h-CLAT), J Toxicol Sci. 2019;44(4):283-297.
Fujita M, Yamamoto Y, Watanabe S, Sugawara T, Wakabayashi K, Tahara Y, Horie N, Fujimoto K, Kusakari K, Kurokawa Y, Kawakami T, Kojima K, Sozu T, Nakayama T, Kusao T, Richmond J, Nicole K, Kim BH, Kojima H, Kasahara T, Ono A: The within- and between-laboratory reproducibility and predictive capacity of the in chemico amino acid derivative reactivity assay: Results of validation study implemented in four participating laboratories. J Appl Toxicol. 2019 Nov;39(11):1492-1505.
Kojima H, Sakai Y, Tanaka N: Japanese Contributions to the Development of Alternative Test Methods, Section 2: Contributions From Countries, Regions and Organisations, The History of Alternative Test Methods in Toxicology, Elsevier, Netherlands, 2019, 79-85.
Kojima H, Yamaguchi H, Sozu T, Kleinstreuer N, Chae-Hyung L, Chen W, Watanabe M, Fukuda T, Yamashita K, Takezawa T: Multi-laboratory Validation Study of the Vitrigel-Eye Irritancy Test Method as an Alternative to In Vivo Eye Irritation Testing. Altern Lab Anim. 2019 Jul-Sep;47(3-4):140-157.
Mizoi K, Hosono M, Kojima H, Ogihara T: Establishment of a primary human hepatocyte spheroid system for evaluating metabolic toxicity using dacarbazine under conditions of CYP1A2 induction. Drug Metab Pharmacokinet. 2019 Dec 24. pii: S1347-4367(19)30233-2.
Presentations, Speeches
Kojima H, Kato Y, Sato A, Yamamoto N: Evaluation of Corneal Damage Recovery Using 3-Dimensional Model, 58th annual meeting of SOT（2019.3.12, Baltimore, USA）
Yamaguchi H, Takezawa T, Kojima H: Predictive Capacity of Vitrigel-EIT (Eye Irritancy Test) Method, 58th annual meeting of SOT（2019.3.13, Baltimore, USA）
Kojima H: Japanese plan on safety evaluation of a chemical with non-animal test methods, Toxicology-2019, International Conference on Toxicology and Risk Assessment（2019.3.20, Frankfurt, Germany）
Kojima H: ICCR update for the safety assessment of cosmetic ingredients, workshop on Cosmetic Risk Assessment and Regulatory Application of Non-animal Testing Technology（2019.4.16, Shanghai, China）
Kojima H, Ikarashi Y, Nakada T, Yagami A, Todo H, Hoshino Y, Kubo F, Nishimura J, Nakajima Y, Sakaguchi H, Yamaguchi M, Sugiyama M, Hatao M: Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-Drugs, Dermatology and Cosmetology Conference 2019（2019.5.14, Narita, Japan）
Kojima H: The Japanese Strategy on Chemical Risk Assessment with New Approaches, International symposium of Advancing the Chemical Risk Assessment: New Approaches for a Sustainable Future（2019.5.31, Seoul, Korea）
Kojima H: Use of new approach methods (NAM) in next generation risk assessment (NGRA), 11th World Surfactant Congress（2019.6.4, Munich, Germany）
Kojima H: International activities on regulatory acceptance of the defined approach for skin sensitization, The 46th Annual Meeting of the Japanese Society of Toxicology (2019.6.27, Tokushima, Japan)
Kojima H: 21st Century Toxicology and Regulatory Testing: An Update from East Asia, The 15th International Congress of Toxicology (ICTXV) (2019.7.16, Honolulu, U.S.A)
Kojima H: Safety evaluation of cosmetic ingredients using 3-D models, Conference on Analytical Techniques for Cosmetics (2019.7.25, Chiayi, Taiwan)
Kojima H: Establishment of the Asian Consortium for Three Rs supported by ASCCT, 8th Annual Meeting of the American Society for Cellular and Computational Toxicology (2019.9.25, Gaithersburg, MD, USA)
Kojima H: Asian Consortium for Three Rs, European Society for Alternatives to Animal Testing (EUSAAT) 2019 (2019.10.12, Linz, Austria)
Kojima H: Modern Cosmetic Testing Technology that Alternative to Animal Testing (efficacy, safety evaluation), The 2nd TISTR and JAIMA conjoint conference（2019.11.7, Bangkok, Thailand）
