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Academic activities 2023

2023

Articles

  • Fujita M, Nakashima N, Wanibuchi S , Yamamoto Y, Kojima H, Ono A, Kasahara T. Assessment of commercial polymers with and without reactive groups using amino acid derivative reactivity assay based on both molar concentration approach and gravimetric approach, J Appl Toxicol. 2023;43(3):446-457.
    doi.org/10.1002/jat.4395.
  • Akagi T, Yamada T, Miyazaki H, Taguchi H, Ikeda H, Katoh M, Mura S, Couvreur P, Chetprayoon P, Maniratanachote R, Yoshida H, Ajiro H, Hashimoto K, Ashikaga, T, Kojima H, Akashi M: Validation study for in vitro skin irritation test using reconstructed human skin equivalents constructed by layer-by-layer cell coating technology, J Appl Toxicol.2023. Jan 3. doi:10.1002/jat.4431.
  • Kimura Y, Yasuno R, Iwaki T , Fujimura C , Ohmiya Y , Nakajima Y, Omori T , Corsini E , Inoue T , Rogen EL , Kojima H , Aiba S: An international validation study of the interleukin-2 luciferase leukocyte toxicity test (IL-2 Luc LTT) to evaluate potential immunosuppressive chemicals and its performance after use with the interleukin-2 luciferase assay (IL-2 Luc assay), Toxicol In Vitro. 2023;88:105535. doi: 10.1016/j.tiv.2022.105535.
  • Ashikaga T, Narita K, Kobayashi M, Tachibana S, Murasaki W, Suzuki M, Ambe K, Tohkin M: Skin Sensitization Potency Prediction of Ingredients in Hair Colorants Using in silico Models of Machine Learning, Journal of Japanese Cosmetic Science Society,2023:47(1), 1–5.
  • Strickland J, Haugabrooks E, Allen DG, Balottin LB, Hirabayashi Y, Kleinstreuer NC, Kojima H, Nishizawa C, Prieto P, Ratzlaff DE, Jeong J, Lee J, Yang Y, Lin P, Sullivan K, Casey W: International regulatory uses of acute systemic toxicity data and integration of new approach methodologies,Crit Rev Toxicol. 2023;53(7):385-411. doi: 10.1080/10408444.2023.2240852.
  • Tanabe I, Yoshida K, Ishikawa S, Ishimori K, Hashizume T, Yoshimoto T, Ashikaga T: Development of an In Vitro Sensitisation Test Using a Coculture System of Human Bronchial Epithelium and Immune Cells, Altern Lab Anim. 2023:2611929231204823. doi: 10.1177/02611929231204823.
  • Mizumachi H,Watanabe M, Ikezumi M, Kajiwara M, Yasuda M, Mizuno M, Imai N, Sakuma M, Shibata M, Watanabe S, Motoyama J, Basketter D, Eskes C, Hoffmann S, Lehmann D, Ashikaga T, Sozu T, Takeyoshi M, Suzuki S, Miyazawa M, Kojima H: The inter-laboratory validation study of EpiSensA for predicting skin sensitization potential, J Appl Toxicol. 2023 Oct 28. doi: 10.1002/jat.4559.

Presentations, Speeches

  • Ashikaga T: Exploration of the MAT in Japan, EDQM-EPAA Pyrogenicity Event(2023.2.15, Brussels, Belgium)
  • Reinke EN, Corsini E, Ono A, Fukuyama T, Ashikaga T, Gerberick GF: Peer Review Report of the EpiSensA Skin Sensitization Assay, SOT 62nd Annual Meeting(2023.3.21, Nashville, USA)
  • Ashikaga T, Ohno A, Nishida A, Iijima K: Development of toxicity evaluation method for nanomaterials using activation of THP-1 cell as an index, SOT 62nd Annual Meeting(2023.3.22, Nashville, USA)
  • Ashikaga T: Current status in Japan, 2nd Microphysiological systems (MPS) World Summit (2023.6.28, Berlin, Germany)
  • Ohno A, Nishida A, Okiyama Y, Iijima K, Ashikaga T: Verification of the effectiveness of EC 200 and EC 150 indicators of THP-1 cell activation on various nanomaterials, 266th ACS National Meeting & Exposition (2023.8.13-17, San Francisco, USA)
  • Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Sugiyama M, Yamamoto K, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M: A step-by-step approach for assessing acute oral toxicity without animal testing for cosmetic ingredients, 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12) (2023.8.28, Niagara Falls, Canada)
  • Todo H, Hatao M, Sakai Y, Kojima H: Latest activities and future directions of JSAAE for Asian cooperation toward 3Rs, 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12) (2023.8.29, Niagara Falls, Canada)
  • Hirabayashi Y, Kojima H, Ashikaga T: Update on recent activities at JaCVAM, 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12) (2023.8.31, Niagara Falls, Canada)
  • Kojima H: Alternative methods in ICH S5 Guidelines for reproductive and developmental toxicity research and their application, 2023 (The 6th) International Conference on Toxicity Testing Alternatives and Translational Toxicology (2023.9.18, Changsha, China)
  • Ashikaga T: International standardization policy for MPS in Japan and development of in vitro respiratory toxicity test as an example of applied research, The 6th Symposium on Organoids and Organs-on-Chips (2023.11.24, Nanjing, China)

Presentation